镇静剂|治疗帕金森：大脑深处，一颗核桃大小的谜团( 七 ) 谜团|运动|理论|Brodie|研究|帕金

[8] Zecca L, Pifl C, Fahn S, Sulzer D, Fariello RG. Oleh Hornykiewicz, a giant in the understanding and treatment of Parkinson disease. NPJ Parkinsons Dis. 2021 Jan 4;7(1):1. doi: 10.1038/s41531-020-00149-4. PMID: 33397996; PMCID: PMC7782676.
[9] Birkmayer W, Hornykiewicz O. The effect of l-3,4-dihydroxyphenylalanine (= DOPA) on akinesia in parkinsonism. 1961. Wien Klin Wochenschr. 2001 Nov 15;113(22):851-4. English, German. PMID: 11763859.
[10] Sano H. Biochemistry of the extrapyramidal system Shinkei Kennkyu No Shinpo, Advances in Neurological Sciences. (ISSN 0001-8724) Tokyo, October 1960;5:42-48. English Translation: Parkinsonism Relat Disord. 2000 Jan;6(1):3-6. doi: 10.1016/s1353-8020(99)00046-2. PMID: 18591145.
[11] Barbeau A, Sourkes TL, Murphy GF (1962) Les catecholamines dans la maladie de Parkinson. In: Monoamines et Système nedrveux central. Georg et Cie S.A., Génève, pp 247–262
[12] Cotzias GC, Van Woert MH, Schiffer LM. Aromatic amino acids and modification of parkinsonism. N Engl J Med. 1967 Feb 16;276(7):374-9. doi: 10.1056/NEJM196702162760703. PMID: 5334614.
[13] Cotzias GC, Papavasiliou PS, Gellene R. Modification of Parkinsonism--chronic treatment with L-dopa. N Engl J Med. 1969 Feb 13;280(7):337-45. doi: 10.1056/NEJM196902132800701. PMID: 4178641.
[14] Rajput AH. An open letter to the Committee on The Nobel Prize in Medicine. Parkinsonism Relat Disord. 2001 Apr;7(2):149-55. doi: 10.1016/s1353-8020(00)00082-1. PMID: 18591152.
[15] Schlossmacher MG, Graybiel AM. Conversations With Dr. Oleh Hornykiewicz, Founding Father of the Dopamine Era in Parkinson's: How Do You Wish to Be Remembered? Mov Disord. 2020 Nov;35(11):1922-1932. doi: 10.1002/mds.28316. Epub 2020 Oct 14. PMID: 33053225; PMCID: PMC7756664.
[16] Plotkin JL, Day M, Surmeier DJ. Synaptically driven state transitions in distal dendrites of striatal spiny neurons. Nat Neurosci. 2011 Jun 12;14(7):881-8. doi: 10.1038/nn.2848. PMID: 21666674; PMCID: PMC3235762.
[17] Horn A, Ewert S, Alho EJL, Axer M, Heinsen H, Fonoff ET, Polimeni JR, Herrington TM. Teaching NeuroImages: In vivo visualization of Edinger comb and Wilson pencils. Neurology. 2019 Apr 2;92(14):e1663-e1664. doi: 10.1212/WNL.0000000000007252. PMID: 30936236; PMCID: PMC6448452.
[18] Gerfen, C. Indirect-pathway neurons lose their spines in Parkinson disease. Nat Neurosci 9, 157–158 (2006). https://doi.org/10.1038/nn0206-157
[19] Kravitz AV, Freeze BS, Parker PR, Kay K, Thwin MT, Deisseroth K, Kreitzer AC. Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature. 2010 Jul 29;466(7306):622-6. doi: 10.1038/nature09159. Epub 2010 Jul 7. PMID: 20613723; PMCID: PMC3552484.
[20] Weingarten HL. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): one designer drug and serendipity. J Forensic Sci. 1988 Mar;33(2):588-95. PMID: 3259617.
[21] Bergman H, Wichmann T, DeLong MR. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science. 1990 Sep 21;249(4975):1436-8. doi: 10.1126/science.2402638. PMID: 2402638.
[22] Limousin P, Krack P, Pollak P, Benazzouz A, Ardouin C, Hoffmann D, Benabid AL. Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med. 1998 Oct 15;339(16):1105-11. doi: 10.1056/NEJM199810153391603. PMID: 9770557.
[23] Bell CC, Han VZ, Sugawara Y, Grant K. Synaptic plasticity in a cerebellum-like structure depends on temporal order. Nature. 1997 May 15;387(6630):278-81. doi: 10.1038/387278a0. PMID: 9153391.
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_原题《治疗帕金森：大脑深处，一颗核桃大小的谜团》
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